Introduction:  Safe injection is a kind of injection that not hurts the one who receives service, not injures the providers and its leftovers won't make harm or damage to the society and environment. The purpose of this study was to investigate the rate of the observance of the standards with safe injection in the inpatient units of teaching hospitals in Tabriz.

Materials and Methods: In this cross-sectional study, 399 samples were examined by Cochran formula. Samples were selected randomly as clusters from each hospital and inpatient units and data were gathered in all three working shifts. The data collection tools used in this study was a checklist which its reliability has been proved. Data were analyzed by using the SPSS 21 and were reported by relevant analytic and descriptive statistics.

Results: 73.4% of subjects were woman. 63.90% of people in the past year have been passed the course related to infection and safe injections. The observance of the standards of safe injection in “preparation phase”, “during the injection” and “after injection” was 64.84, 58.95, and 63.95%, respectively, which had in fairly good condition. 

Conclusions: Performing the retraining programs in injections and nosocomial infections, employing people with work experiences in teaching hospitals, providing individual protection equipment such as glasses and mask, educations about hand washing, providing and using auto disable syringes and safety boxes and immunizing the staffs against hepatitis B and C can be the most important actions in doing safe injection.