Journal of Patient Safety & Quality Improvement

Journal of Patient Safety & Quality Improvement

SARS-CoV-2 PCR-Positive Infection Rates and COVID-19 Vaccination Patterns Among Healthcare Workers at Imam Khomeini Hospital, Ardabil, Iran: A Cross-Sectional Study (March 2019–March 2023)

Document Type : Original Article

Authors
Vahid Adiban 1
Mohammad Hasanpour-darghah 1
Faezeh Hazeri 2
1 Department of Anesthesiology, School of Medicine, Ardabil University of Medical Sceinces, Ardabil, Iran.
2 School of Medicine, Ardabil University of Medical Sceinces, Ardabil, Iran.
10.22038/psj.2025.84446.1450
Abstract
Introduction:
The spread of the Covid-19 virus, especially among medical personnel, has caused serious concerns in the field of public health. Vaccination has been considered as a key strategy to reduce the incidence and severity of the disease. The purpose of this study is to determine the rate of PCR-positive corona and the number and type of corona vaccine received by the medical personnel of the corona department of Imam Khomeini Hospital in Ardabil during March 2019 to March 2023.
 Materials and Methods:
In this study, the rate of infection with covid-19 and hospitalization in medical personnel was investigated in relation to the number and type of vaccines received. The information collected included the history of corona infection, the type and number of vaccines, and the hospitalization status.
 Results:
The results showed that 70.12% of the participants were infected with Covid-19 before vaccination and 65.85% after it. People who had received more vaccines had less severe disease. Also, only 7.10% of people had a history of hospitalization due to COVID-19.
 Conclusion:
This study emphasizes that vaccination is an important tool in reducing the incidence and severity of covid-19 disease. According to the results, it is suggested to pay more attention to the number and type of vaccines received in order to protect the health of medical personnel and society.
Keywords
Vaccine
medical personnel
PCR
COVID-19
Subjects
  1. Cui J, Li F, Shi Z-L. Origin and evolution of pathogenic coronaviruses. Nature reviews microbiology. 2019;17(3):181-92.
  2. Di Mascio D, Khalil A, Saccone G, Rizzo G, Buca D, Liberati M, et al. Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. American journal of obstetrics & gynecology MFM. 2020;2(2):100107.
  3. Esakandari H, Nabi-Afjadi M, Fakkari-Afjadi J, Farahmandian N, Miresmaeili S-M, Bahreini E. A comprehensive review of COVID-19 characteris- tics. Biological procedures online. 2020; 22:1-10.
  4. Pascarella G, Strumia A, Piliego C, Bruno F, Del Buono R, Costa F, et al. COVID‐19 diagnosis and management: a comprehensive review. Journal of internal medicine. 2020;288(2):192-206.
  5. Singhal T. A review of coronavirus disease-2019 (COVID-19). The indian journal of pediatrics. 2020;87(4):281-6.
  6. Kowalik MM, Trzonkowski P, Łasińska-Kowara M, Mital A, Smiatacz T, Jaguszewski M. COVID-19-Toward a comprehensive understand- ding of the disease. Cardiology journal. 2020; 27(2):99-114.
  7. Tahamtan A, Ardebili A. Real-time RT-PCR in COVID-19 detection: issues affecting the results. Expert review of molecular diagnostics. 2020; 20(5):453-4.
  8. Organization WH. Draft landscape of COVID-19 candidate vaccines. 2020.
  9. Dolgin E. Pan-coronavirus vaccine pipeline takes form. Nat Rev Drug Discov. 2022; 21(5): 324-6.
  10. Haynes BF, Corey L, Fernandes P, Gilbert PB, Hotez PJ, Rao S, et al. Prospects for a safe COVID-19 vaccine. Science translational medicine. 2020;12(568): eabe0948.
  11. Kaur SP, Gupta V. COVID-19 Vaccine: A comprehensive status report. Virus research. 2020; 288:198114.
  12. Le TT, Andreadakis Z, Kumar A, Román RG, Tollefsen S, Saville M, et al. The COVID-19 vaccine development landscape. Nat Rev Drug Discov. 2020; 19(5):305-6.
  13. Basiri N, Koushki M. Study of vaccine production abroad and scientific and research challenges of COVID-19 vaccine production in Iran. Annals of the Romanian Society for Cell Biology. 2021:17249-56.
  14. Zaher K, Basingab F, Alrahimi J, Basahel K, Aldahlawi A. Gender differences in response to COVID-19 infection and vaccination. Biomedicines. 2023;11(6):1677.
  15. Bandyopadhyay S, Baticulon RE, Kadhum M, Alser M, Ojuka DK, Badereddin Y, et al. Infection and mortality of healthcare workers worldwide from COVID-19: a systematic review. BMJ global health. 2020;5(12):e003097.
  16. Thomeer MB. Relationship status-based health disparities during the COVID-19 pandemic. Social currents. 2023;10(1):17-40.
  17. Tartof SY, Slezak JM, Puzniak L, Hong V, Frankland TB, Ackerson BK, et al. Effectiveness of a third dose of BNT162b2 mRNA COVID-19 vaccine in a large US health system: a retrospective cohort study. The Lancet Regional Health–Americas. 2022;9.
  18. Paul P, El-Naas A, Hamad O, Salameh MA, Mhaimeed N, Laswi I, et al. Effectiveness of the pre-Omicron COVID-19 vaccines against Omicron in reducing infection, hospitalization, severity, and mortality compared to Delta and other variants: A systematic review. Human Vaccines & Immunotherapeutics. 2023;19(1):2167410.
  19. Dadras O, SeyedAlinaghi S, Karimi A, Shojaei A, Amiri A, Mahdiabadi S, et al. COVID-19 vaccines’ protection over time and the need for booster doses; a systematic review. Archives of Academic Emergency Medicine. 2022;10(1).
  20. Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. New England journal of medicine. 2020; 383(27): 2603-15.
  21. Fatima S, Zafar A, Afzal H, Ejaz T, Shamim S, Saleemi S, et al. COVID-19 infection among vaccinated and unvaccinated: Does it make any difference? PloS one. 2022;17(7): e0270485.

 

Journal of Patient Safety & Quality Improvement
Volume 13, Issue 2
Spring 2025
Pages 121-126