Atypical Presentation of Hypothyroidism Mimicking Rheumatism: A Case Report

Document Type : Case Report

Authors

1 Associate Professor of Endocrinology, Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Professor of Neurology, Department of Neurology, Mashhad University of Medical Science, Mashhad, Iran.

3 Student of Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. 5Clinical Research Development Unit, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

10.22038/psj.2024.83897.1448

Abstract

Introduction:
Hypothyroidism typically manifests as tiredness, somnolence, weight gain, cold intolerance, hair loss, menstrual abnormalities, and musculoskeletal symptoms. Non-specific musculoskeletal symptoms are common and impair the patient’s quality of life. Hypothyroid myopathy has been described as fatigue, myalgia, cramps, stiffness, myoedema, and weakness.
 
Case Report:
 Here, we present a patient with muscular cramps and numbness of the toes, initially diagnosed with rheumatism. After a year of treatment with no positive results, the patient was diagnosed with hypothyroidism due to abnormal levels of thyroid hormone. Three months after treatment with levothyroxine, the patient experienced a complete resolution of symptoms.
 
Conclusion:
This particular case underscores the crucial need to consider hypothyroidism as a differential diagnosis in all patients with unexplained musculoskeletal symptoms. By doing so, we can avoid potential misdiagnoses and ensure timely and effective treatment.

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Main Subjects

References

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Journal of Patient Safety & Quality Improvement
Volume 12, Issue 4
October 2024
Pages 203-206

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