Relationship Between Body Mass Index (BMI) and Kidney Stones in Children

Document Type : Original Article

Authors

1 Department of Pediatrics, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.

2 Department of Community Medicine and Biostatistics, School of Medicine, Ardabil University of Medical sciences, Ardabil, Iran.

10.22038/psj.2024.83291.1444

Abstract

Introduction:
A widespread and significant problem in pediatric medicine, kidney and urinary tract stones are becoming more common as a result of sedentary lifestyles, poor diets, wrong fluid intake patterns, and improper medication use.
 
Materials and Methods:
Children referred to Ardabil City's Kowsar Clinic received sonography and a clinical assessment. In this investigation, 91 children with normal sonography were chosen as the control group, and 91 children with kidney stones identified by sonography were chosen as the case group. The association between kidney stones and BMI was examined analytically using logistic single and multiple-variable regression models, and the odds ratio was shown.
 
Results:
182 people were analyzed in this study, 50% in the case group and 50% in the control group. Children had one stone at the highest rate (57.1%). According to the multiple variable logistic model, the body mass index has an odds ratio of 0.99. Additionally, a statistically significant gender study revealed that women are 2.29 times more likely than men to have kidney stones. Furthermore, compared to children over ten, children under five have a 4.14-fold increased risk of kidney stones, according to age analysis.
 
Conclusion:
These findings indicate that kidney stones and body mass index do not significantly correlate. Kidney stones are more likely to occur in girls than in boys, and in children younger than five.
 

Keywords

Main Subjects


  1. Tasian GE, Copelovitch L. Evaluation and medical management of kidney stones in children. The Journal of urology. 2014; 192(5): 1329-36.
  2. Sas DJ, Hulsey TC, Shatat IF, Orak JK. Increasing incidence of kidney stones in children evaluated in the emergency department. The Journal of pediatrics. 2010;157(1):132-7.
  3. Dwyer ME, Krambeck AE, Bergstralh EJ, Milliner DS, Lieske JC, Rule AD. Temporal trends in incidence of kidney stones among children: a 25-year population based study. The Journal of urology. 2012;188(1):247-52.
  4. Poore W, Boyd CJ, Singh NP, Wood K, Gower B, Assimos DG. Obesity and its impact on kidney stone formation. Reviews in urology. 2020; 22(1): 17.
  5. Taylor EN, Stampfer MJ, Curhan GC. Obesity, weight gain, and the risk of kidney stones. Jama. 2005;293(4):455-62.
  6. Carbone A, Al Salhi Y, Tasca A, Palleschi G, Fuschi A, De Nunzio C, et al. Obesity and kidney stone disease: a systematic review. The Italian journal of urology and nephrology. 2018; 70(4): 393-400.
  7. Hess B. Metabolic syndrome, obesity and kidney stones. Arab journal of urology. 2012; 10(3):258-64.
  8. Sarica K. Medical aspect and minimal invasive treatment of urinary stones in children. Archivio italiano di urologia andrologia. 2008; 80(2): 43.
  9. Abiri B, Ahmadi AR, Amini S, Akbari M, Hosseinpanah F, Madinehzad SA, et al. Prevalence of overweight and obesity among Iranian population: a systematic review and meta-analysis. Journal of Health, Population and Nutrition. 2023;42(1):70.
  10. Siener R, Glatz S, Nicolay C, Hesse A. The role of overweight and obesity in calcium oxalate stone formation. Obesity research. 2004; 12(1): 106-13.
  11. Taylor EN, Curhan GC. Body size and 24-hour urine composition. American Journal of Kidney Diseases. 2006;48(6):905-15.
  12. DeFOOR W, Asplin J, Jackson E, Jackson C, Reddy P, Sheldon C, et al. Results of a prospective trial to compare normal urine supersaturation in children and adults. The Journal of urology. 2005; 174(4 Part 2):1708-10.
  13. Eisner BH, Eisenberg ML, Stoller ML. Influence of body mass index on quantitative 24-hour urine chemistry studies in children with nephrolithiasis. The Journal of urology. 2009; 182(3):1142-6.
  14. Kieran K, Giel DW, Morris BJ, Wan JY, Tidwell CD, Giem A, et al. Pediatric urolithiasis—does body mass index influence stone presentation and treatment? The Journal of urology. 2010;184(4S):1810-5.
  15. Kim SS, Luan X, Canning DA, Landis JR, Keren R. Association between body mass index and urolithiasis in children. The Journal of urology. 2011;186(4):1734-9.
  16. Sarica K, Eryıldırım B, Yencilek F, Kuyumcuoglu U. Role of overweight status on stone-forming risk factors in children: a prospective study. Urology. 2009;73(5):1003-7.
  17. Novak TE, Lakshmanan Y, Trock BJ, Gearhart JP, Matlaga BR. Sex prevalence of pediatric kidney stone disease in the United States: an epidemiologic investigation. Urology. 2009; 74(1):104-7.
  18. Lieske J, De La Vega LP, Slezak J, Bergstralh E, Leibson C, et al. Renal stone epidemiology in Rochester, Minnesota: an update. Kidney international. 2006;69(4):760-4.
  19. Stamatelou KK, Francis ME, Jones CA, Nyberg Jr LM, Curhan GC. Time trends in reported prevalence of kidney stones in the United States: 1976–1994. Kidney international. 2003; 63(5):1817-23.
  20. Curhan GC. Epidemiology of stone disease. Urologic Clinics of North America. 2007; 34(3): 287-93.